RT Journal Article
T1 Meat and haem iron intake in relation to glioma in the European Prospective Investigation into Cancer and Nutrition study.
A1 Ward, Heather A
A1 Gayle, Alicia
A1 Jakszyn, Paula
A1 Merritt, Melissa
A1 Melin, Beatrice
A1 Freisling, Heinz
A1 Weiderpass, Elisabete
A1 Tjonneland, Anne
A1 Olsen, Anja
A1 Dahm, Christina C
A1 Overvad, Kim
A1 Katzke, Verena
A1 Kühn, Tilman
A1 Boeing, Heiner
A1 Trichopoulou, Antonia
A1 Lagiou, Pagona
A1 Kyrozis, Andreas
A1 Palli, Domenico
A1 Krogh, Vittorio
A1 Tumino, Rosario
A1 Ricceri, Fulvio
A1 Mattiello, Amalia
A1 Bueno-de-Mesquita, Bas
A1 Peeters, Petra H
A1 Quirós, José Ramón
A1 Agudo, Antonio
A1 Rodriguez-Barranco, Miguel
A1 Larrañaga, Nerea
A1 Huerta, José M
A1 Barricarte, Aurelio
A1 Sonestedt, Emily
A1 Drake, Isabel
A1 Sandström, Maria
A1 Travis, Ruth C
A1 Ferrari, Pietro
A1 Riboli, Elio
A1 Cross, Amanda J
AB Diets high in red or processed meat have been associated positively with some cancers, and several possible underlying mechanisms have been proposed, including iron-related pathways. However, the role of meat intake in adult glioma risk has yielded conflicting findings because of small sample sizes and heterogeneous tumour classifications. The aim of this study was to examine red meat, processed meat and iron intake in relation to glioma risk in the European Prospective Investigation into Cancer and Nutrition study. In this prospective cohort study, 408 751 individuals from nine European countries completed demographic and dietary questionnaires at recruitment. Multivariable Cox proportional hazards models were used to examine intake of red meat, processed meat, total dietary iron and haem iron in relation to incident glioma. During an average follow-up of 14.1 years, 688 incident glioma cases were diagnosed. There was no evidence that any of the meat variables (red, processed meat or subtypes of meat) or iron (total or haem) were associated with glioma; results were unchanged when the first 2 years of follow-up were excluded. This study suggests that there is no association between meat or iron intake and adult glioma. This is the largest prospective analysis of meat and iron in relation to glioma and as such provides a substantial contribution to a limited and inconsistent literature.
YR 2018
FD 2018
LK http://hdl.handle.net/10668/10605
UL http://hdl.handle.net/10668/10605
LA en
DS RISalud
RD Apr 7, 2025