RT Journal Article
T1 Brain networks of temporal preparation: A multiple regression analysis of neuropsychological data
A1 Trivino, Monica
A1 Correa, Angel
A1 Lupianez, Juan
A1 Jesus Funes, Maria
A1 Catena, Andres
A1 He, Xun
A1 Humphreys, Glyn W.
K1 Temporal preparation
K1 Temporal orienting
K1 Foreperiod
K1 Regression analysis
K1 Temporal lobe
K1 Reaction-time
K1 Orienting attention
K1 Executive functions
K1 Anterior cingulate
K1 Functional-anatomy
K1 Prefrontal cortex
K1 Neural mechanisms
K1 Perception
K1 Foreperiod
K1 Deficit
AB There are only a few studies on the brain networks involved in the ability to prepare in time, and most of them followed a correlational rather than a neuropsychological approach. The present neuropsychological study performed multiple regression analysis to address the relationship between both grey and white matter (measured by magnetic resonance imaging in patients with brain lesion) and different effects in temporal preparation (Temporal orienting, Foreperiod and Sequential effects). Two versions of a temporal preparation task were administered to a group of 23 patients with acquired brain injury. In one task, the cue presented (a red versus green square) to inform participants about the time of appearance (early versus late) of a target stimulus was blocked, while in the other task the cue was manipulated on a trial-by-trial basis. The duration of the cue-target time intervals (400 versus 1400 ms) was always manipulated within blocks in both tasks. Regression analysis were conducted between either the grey matter lesion size or the white matter tracts disconnection and the three temporal preparation effects separately. The main finding was that each temporal preparation effect was predicted by a different network of structures, depending on cue expectancy. Specifically, the Temporal orienting effect was related to both prefrontal and temporal brain areas. The Foreperiod effect was related to right and left prefrontal structures. Sequential effects were predicted by both parietal cortex and left subcortical structures. These findings show a clear dissociation of brain circuits involved in the different ways to prepare in time, showing for the first time the involvement of temporal areas in the Temporal orienting effect, as well as the parietal cortex in the Sequential effects. (C) 2016 Elsevier Inc. All rights reserved.
PB Academic press inc elsevier science
SN 1053-8119
YR 2016
FD 2016-11-15
LK http://hdl.handle.net/10668/18846
UL http://hdl.handle.net/10668/18846
LA en
DS RISalud
RD Apr 12, 2025