RT Journal Article T1 Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis. A1 Oncina-Canovas, Alejandro A1 Vioque, Jesus A1 Gonzalez-Palacios, Sandra A1 Martínez-González, Miguel Angel A1 Salas-Salvado, Jordi A1 Corella, Dolores A1 Zomeño, Dolores A1 Martinez, J Alfredo A1 Alonso-Gomez, Angel M A1 Wärnberg, Julia A1 Romaguera, Dora A1 Lopez-Miranda, Jose A1 Estruch, Ramon A1 Bernal-Lopez, Rosa M A1 Lapetra, Jose A1 Serra-Majem, J Luís A1 Bueno-Cavanillas, Aurora A1 Tur, Josep A A1 Martin-Sanchez, Vicente A1 Pinto, Xavier A1 Delgado-Rodriguez, Miguel A1 Matia-Martin, Pilar A1 Vidal, Josep A1 Vazquez, Clotilde A1 Daimiel, Lidia A1 Ros, Emili A1 Toledo, Estefania A1 Babio, Nancy A1 Sorli, Jose V A1 Schröder, Helmut A1 Zulet, Maria Angeles A1 Sorto-Sanchez, Carolina A1 Baron-Lopez, Francisco Javier A1 Compañ-Gabucio, Laura A1 Morey, Marga A1 Garcia-Rios, Antonio A1 Casas, Rosa A1 Gomez-Perez, Ana Maria A1 Santos-Lozano, Jose Manuel A1 Vazquez-Ruiz, Zenaida A1 Nishi, Stephanie K A1 Asensio, Eva M A1 Soldevila, Nuria A1 Abete, Itziar A1 Goicolea-Güemez, Leire A1 Buil-Cosiales, Pilar A1 Garcia-Gavilan, Jesus F A1 Canals, Erik A1 Torres-Collado, Laura A1 Garcia-de-la-Hera, Manuela K1 Cardiometabolic risk K1 Dietary food patterns K1 Metabolic syndrome K1 Pro-vegetarian AB We explored the cross-sectional association between the adherence to three different provegetarian (PVG) food patterns defined as general (gPVG), healthful (hPVG) and unhealthful (uPVG), and the cardiometabolic risk in adults with metabolic syndrome (MetS) of the PREDIMED-Plus randomized intervention study. We performed a cross-sectional analysis of baseline data from 6439 participants of the PREDIMED-Plus randomized intervention study. The gPVG food pattern was built by positively scoring plant foods (vegetables/fruits/legumes/grains/potatoes/nuts/olive oil) and negatively scoring, animal foods (meat and meat products/animal fats/eggs/fish and seafood/dairy products). The hPVG and uPVG were generated from the gPVG by adding four new food groups (tea and coffee/fruit juices/sugar-sweetened beverages/sweets and desserts), splitting grains and potatoes and scoring them differently. Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. A higher adherence to the gPVG and hPVG was associated with lower cardiometabolic risk in multivariable models. The regression coefficients for 5th vs. 1st quintile were - 0.16 (95% CI: - 0.33 to 0.01) for gPVG (p trend: 0.015), and - 0.23 (95% CI: - 0.41 to - 0.05) for hPVG (p trend: 0.016). In contrast, a higher adherence to the uPVG was associated with higher cardiometabolic risk, 0.21 (95% CI: 0.04 to 0.38) (p trend: 0.019). Higher adherence to gPVG and hPVG food patterns was generally associated with lower cardiovascular risk, whereas higher adherence to uPVG was associated to higher cardiovascular risk. PB Springer YR 2021 FD 2021-07-19 LK http://hdl.handle.net/10668/18342 UL http://hdl.handle.net/10668/18342 LA en NO Oncina-Cánovas A, Vioque J, González-Palacios S, Martínez-González MÁ, Salas-Salvadó J, Corella D, et al. Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis. Eur J Nutr. 2022 Feb;61(1):357-372 DS RISalud RD Apr 12, 2025