RT Journal Article T1 Physicochemical characteristics and antiproliferative and antioxidant activities of Moroccan Zantaz honey rich in methyl syringate. A1 Elamine, Youssef A1 Lyoussi, Badiaa A1 Miguel, Maria G A1 Anjos, Ofélia A1 Estevinho, Letícia A1 Alaiz, Manuel A1 Girón-Calle, Julio A1 Martín, Jesús A1 Vioque, Javier K1 Antioxidant activity K1 Antiproliferative activity K1 Methyl syringate K1 Zantaz honey AB Zantaz honey is a monofloral variety produced from the melliferous plant Bupleurum spinosum (Apiaceae), a shrub that grows mainly in the Atlas Moroccan Mountains. Determination of the polyphenol composition revealed that methyl syringate accounts for more than 50% of total polyphenols, which represents a very useful parameter for the characterization of this monofloral honey. Epicatechin, syringic acid and catechin are also abundant. Caco-2 and THP-1 cells were used for determination of antioxidant and antiproliferative activities in Zantaz honey, respectively. All six commercial samples that were used for these studies exhibited antioxidant activity and inhibited cell proliferation. Interestingly, these activities had a positive correlation mainly with the content in methyl syringate and gallic acid. The recognition of health promoting activities in Zantaz honey should increase its commercial value, which would have a positive economic impact on the poor rural communities of Morocco where it is produced. YR 2020 FD 2020-09-16 LK http://hdl.handle.net/10668/16552 UL http://hdl.handle.net/10668/16552 LA en DS RISalud RD Apr 17, 2025