TY  - JOUR
AU  - Montilla-Garcia, Angeles
AU  - Tejada, Miguel A
AU  - Ruiz-Cantero, M Carmen
AU  - Bravo-Caparros, Inmaculada
AU  - Yeste, Sandra
AU  - Zamanillo, Daniel
AU  - Cobos, Enrique J
PY  - 2019
DO  - 10.3389/fphar.2019.00136
SN  - 1663-9812
UR  - http://hdl.handle.net/10668/13683
T2  - Frontiers in pharmacology
AB  - Sigma-1 receptor antagonism increases the effects of morphine on nociceptive pain, even in morphine-tolerant animals. However, it is unknown whether these receptors are able to modulate morphine antinociception and tolerance during inflammatory pain....
LA  - en
PB  - Frontiers Research Foundation
KW  - analgesia
KW  - grip strength
KW  - joint inflammation
KW  - morphine
KW  - pain
KW  - sigma-1 receptors
KW  - tolerance
KW  - von Frey threshold
KW  - Mice
KW  - Animals
KW  - Hyperalgesia
KW  - Morphine
KW  - Analgesics, Opioid
KW  - morphine-3-glucuronide
KW  - Hot Temperature
KW  - Nociception
KW  - Analgesics
KW  - Morphine Derivatives
KW  - Inflammation
KW  - Analgesia
KW  - Nociceptive Pain
KW  - Hand Strength
KW  - Brain
TI  - Modulation by Sigma-1 Receptor of Morphine Analgesia and Tolerance: Nociceptive Pain, Tactile Allodynia and Grip Strength Deficits During Joint Inflammation.
TY  - research article
VL  - 10
ER  -