%0 Journal Article %A Paredes, Igor %A Castano Leon, Ana Maria %A Lagares, Alfonso %A Jimenez Roldan, Luis %A Perez-Nunez, Angel %A Gonzalez-Leon, Pedro %A Delgado-Fernandez, Juan %A Eiriz, Carla %A Garcia-Perez, Daniel %A Miguel Moreno-Gomez, Luis %A Esteban-Sinovas, Olga %A Delgado-Lopez, Pedro %A Martin-Alonso, Javier %A Kaen, Ariel %A Tirado-Caballero, Jorge %A Ordonez Carmona, Marta %A Arteaga Romero, Francisco %A Gonzalez Pombo, Marta %A Alen, Jose F. %A Gil-Simoes, Ricardo %A Torres, Cristina, V %A Navas Garcia, Marta %A Blasco, Guillermo %A Frade-Porto, Natalia %A Gonzalez-Tarno, Patricia %A Martin Segura, Adrian %A Gelabert-Gonzalez, Miguel %A Menendez Cortezon, Beatriz %A Rodriguez Botana, Brais %A Perez-Alfayate, Rebeca %A Fernandez Garcia, Carla %A Ferrandez Pujante, Borja %A Vargas-Jimenez, Andres %A Cotua, Carlos %A de la Lama, Adolfo %A Calero, Lourdes %A Ruiz-Juretschke, Fernando %A Garcia Leal, Roberto %A Valera Mele, Marc %A Casitas Hernando, Vicente %A Rivero Martin, Belen %A Orduna, Javier %A Casado Pellejero, Juan %A Fustero De Miguel, David %A Diaz-Molina, Jorge %A Moles Herbera, Jesus %A Castello Ruiz, Maria Jose %A Gomar Alba, Mario %A Garcia Perez, Fernando %A Hernandez Garcia, Borja Jesus %A Villasenor Ledezma, Javier %A Otero Rodriguez, Alvaro %A Jose Ailagas, Juan %A Goncalves-Estella, Jesus %A Sousa Casasnovas, Pablo %A Pascual Argente, Daniel %A Ruiz Martin, Laura %A Roa Montes de Oca, Juan Carlos %A Arandia Guzman, Daniel %A Garcia Martin, Andoni %A Torres Carretero, Luis %A Garrido Ruiz, Patricia Alejandra %A Calvo, Marta %A Miranda-Lloret, Pablo %A Rodriguez-Cadarso Suarez-Vence, Miguel %A Anotn Oltra, Joan %A Roca Barber, Amparo %A Quiroz Tejada, Arnold %A Carbayo Lozano, Guillermo %A Bermudez Vilar, Garazi %A Paternain Martin, Clara %A Dela FuenteVilla, Pablo %A Fidalgo De la Rosa, Marina %A Sistiaga Garcia, Inigo L. %A Zabalo San Juan, Gorka %T Impact of the first wave of the SARS-CoV-2 pandemic on the outcome of neurosurgical patients: a nationwide study in Spain %D 2021 %@ 2044-6055 %U https://hdl.handle.net/10668/24917 %X Objective To assess the effect of the first wave of the SARS-CoV-2 pandemic on the outcome of neurosurgical patients in Spain. Settings The initial flood of COVID-19 patients overwhelmed an unprepared healthcare system. Different measures were taken to deal with this overburden. The effect of these measures on neurosurgical patients, as well as the effect of COVID-19 itself, has not been thoroughly studied. Participants This was a multicentre, nationwide, observational retrospective study of patients who underwent any neurosurgical operation from March to July 2020. Interventions An exploratory factorial analysis was performed to select the most relevant variables of the sample. Primary and secondary outcome measures Univariate and multivariate analyses were performed to identify independent predictors of mortality and postoperative SARS-CoV-2 infection. Results Sixteen hospitals registered 1677 operated patients. The overall mortality was 6.4%, and 2.9% (44 patients) suffered a perioperative SARS-CoV-2 infection. Of those infections, 24 were diagnosed postoperatively. Age (OR 1.05), perioperative SARS-CoV-2 infection (OR 4.7), community COVID-19 incidence (cases/10(5) people/week) (OR 1.006), postoperative neurological worsening (OR 5.9), postoperative need for airway support (OR 5.38), ASA grade >= 3 (OR 2.5) and preoperative GCS 3-8 (OR 2.82) were independently associated with mortality. For SARS-CoV-2 postoperative infection, screening swab test = 3 (OR 2.5) and preoperative GCS 3-8 (OR 2.82) were independently associated with mortality. For SARS-CoV-2 postoperative infection, screening swab test %K neurosurgery %K neurological injury %K neurological oncology %K adult surgery %~