TY - JOUR AU - Rissin, David M AU - López-Longarela, Barbara AU - Pernagallo, Salvatore AU - Ilyine, Hugh AU - Vliegenthart, A D Bastiaan AU - Dear, James W AU - Díaz-Mochón, Juan J AU - Duffy, David C PY - 2017 DO - 10.1371/journal.pone.0179669 UR - http://hdl.handle.net/10668/11376 T2 - PloS one AB - We have developed a single probe method for detecting microRNA from human serum using single molecule arrays, with sequence specificity down to a single base, and without the use of amplification by polymerases. An abasic peptide nucleic acid (PNA)... LA - en KW - Acetaminophen KW - Adult KW - Base Sequence KW - Biomarkers KW - Case-Control Studies KW - Chemical and Drug Induced Liver Injury KW - Drug Overdose KW - Humans KW - Limit of Detection KW - MicroRNAs KW - Molecular Diagnostic Techniques KW - Nucleic Acid Hybridization KW - Sensitivity and Specificity KW - Young Adult TI - Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury. TY - research article VL - 12 ER -