TY - JOUR AU - El-Hammadi, Mazen M AU - Small-Howard, Andrea L AU - Jansen, Chad AU - Fernández-Arévalo, Mercedes AU - Turner, Helen AU - Martín-Banderas, Lucía PY - 2022 DO - 10.1016/j.ijpharm.2022.121524 UR - http://hdl.handle.net/10668/22270 T2 - International journal of pharmaceutics AB - The objective of these in vitro studies was to investigate the impact of the encapsulation of three cannabis-based terpenes, namely β-myrcene (MC), β-caryophyllene (CPh), and nerolidol (NL), on their potential efficacy in pain management.... LA - en KW - Beta-caryophyllene KW - Beta-myrcene KW - Cannabis-based terpenes KW - Chronic pain KW - Nanomedicine KW - Nerolidol KW - PLGA polymeric nanoparticles KW - Calcium KW - Cannabis KW - Chronic Pain KW - Drug Carriers KW - HEK293 Cells KW - Humans KW - Nanoparticles KW - Particle Size KW - Polyethylene Glycols KW - Polylactic Acid-Polyglycolic Acid Copolymer KW - TRPV Cation Channels KW - Terpenes TI - Potential use for chronic pain: Poly(Ethylene Glycol)-Poly(Lactic-Co-Glycolic Acid) nanoparticles enhance the effects of Cannabis-Based terpenes on calcium influx in TRPV1-Expressing cells. TY - research article VL - 616 ER -