TY - JOUR AU - Al-Aqil, Faten A AU - Monte, Maria J AU - Peleteiro-Vigil, Ana AU - Briz, Oscar AU - Rosales, Ruben AU - González, Raquel AU - Aranda, Carlos J AU - Ocón, Borja AU - Uriarte, Iker AU - de Medina, Fermín Sánchez AU - Martinez-Augustín, Olga AU - Avila, Matías A AU - Marín, José J G AU - Romero, Marta R PY - 2018 DO - 10.1016/j.bbadis.2018.06.003 SN - 0925-4439 UR - http://hdl.handle.net/10668/12564 T2 - Biochimica et biophysica acta. Molecular basis of disease AB - At high doses, glucocorticoids (GC) have been associated with enhanced serum bile acids and liver injury. We have evaluated the effect of GC, in the absence of hepatotoxicity, on FXR/FGF91(Fgf15)/FGF21-mediated ileum-liver crosstalk. Rats and mice... LA - en KW - Cholestasis KW - Gene regulation KW - Intestine KW - Metabolism KW - Transport KW - Animals KW - Autocrine Communication KW - Bile Acids and Salts KW - Cholesterol KW - Cholesterol 7-alpha-Hydroxylase KW - Colitis KW - Disease Models, Animal KW - Female KW - Fibroblast Growth Factors KW - Glucocorticoids KW - Hep G2 Cells KW - Humans KW - Ileum KW - Liver KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Rats KW - Rats, Wistar KW - Receptors, Cytoplasmic and Nuclear KW - Signal Transduction KW - Up-Regulation TI - Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk. TY - research article VL - 1864 ER -