RT Journal Article T1 Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study A1 Perez-Burillo, S. A1 Pastoriza, S. A1 Girones, A. A1 Avellaneda, A. A1 Pilar Francino, M. A1 Rufian-Henares, J. A. K1 Salami K1 Probiotic K1 Citrus fiber K1 Antioxidant capacity K1 Short chain fatty acids K1 Gut microbiota K1 Lactobacillus-rhamnosus hn001 K1 Meat-products K1 Consumption AB A human intervention in 24 healthy volunteers was performed to test the potential health benefits of a fermented salami with a probiotic Lactobacillus rhamnosus HN001 and added citrus fiber. Anthropometric measurements and blood biochemistry did not show any significant differences between pre- and post-intervention during 4 weeks with a daily intake of 30 g of salami, neither with regular salami (control group) nor with reformulated salami (intervention group). However, the inflammatory markers CRP and TNF alpha decreased significantly after intervention, suggesting a less inflammatory environment after reformulated salami consumption. Antioxidant plasmatic markers also improved within the intervention group. Butyrate production was significantly increased after reformulated salami consumption. Gut microbiota community structure, however, was not significantly shaped by neither regular nor reformulated salami. After the intervention with probiotic salami, L. rhamnosus was detected by quantitative polymerase chain reaction (qPCR) in all samples of the intervention group but not in the control group, showing probiotic effect. PB Elsevier BV SN 1756-4646 YR 2020 FD 2020-01-10 LK http://hdl.handle.net/10668/18819 UL http://hdl.handle.net/10668/18819 LA en NO S. Pérez-Burillo, S. Pastoriza, A. Gironés, A. Avellaneda, M. Pilar Francino, J.A. Rufián-Henares, Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study, Journal of Functional Foods, Volume 66, 2020, 103790, DS RISalud RD Apr 6, 2025