TY - JOUR AU - Upton, Alex AU - Trelles, Oswaldo AU - Cornejo-Garcia, Jose Antonio AU - Perkins, James Richard PY - 2015 DO - 10.1093/bib/bbv058 UR - http://hdl.handle.net/10668/10083 T2 - Briefings in bioinformatics AB - It is becoming clear that most human diseases have a complex etiology that cannot be explained by single nucleotide polymorphisms (SNPs) or simple additive combinations; the general consensus is that they are caused by combinations of multiple genetic... LA - en PB - Oxford University Press KW - SNP-interactions KW - Biomarker KW - Disease marker KW - Epistasis KW - Genome sequencing KW - Genotyping KW - High-performance computing KW - Algorithms KW - Epistasis, Genetic KW - Genome KW - Genome-Wide Association Study KW - Humans KW - Polymorphism, Single Nucleotide TI - Review: High-performance computing to detect epistasis in genome scale data sets. TY - research article VL - 17 ER -