TY - JOUR AU - de Miguel-Luken, Maria Jose AU - Chaves-Conde, Manuel AU - Quintana, Begoña AU - Menoyo, Alicia AU - Tirado, Isabel AU - de Miguel-Luken, Verónica AU - Pachon, Jeronimo AU - Chinchon, David AU - Suarez, Vladimir AU - Carnero, Amancio PY - 2016 DO - 10.18632/oncotarget.9172 UR - http://hdl.handle.net/10668/10071 T2 - Oncotarget AB - Current larynx preservation treatments have achieved an improvement of laryngoesophageal dysfunction-free survival (LDS) but lead to significant toxicities and recurrences. At present, there is no evidence to select the group of patients that may... LA - en KW - DDR KW - H2AX KW - Pathology Section KW - biomarker KW - laryngeal cancer KW - laryngeal preservation KW - Antineoplastic Agents KW - Biomarkers, Tumor KW - Carcinoma, Squamous Cell KW - Chemoradiotherapy KW - Cisplatin KW - Disease Progression KW - Disease-Free Survival KW - Dose-Response Relationship, Drug KW - Female KW - Head and Neck Neoplasms KW - Histones KW - Humans KW - Kaplan-Meier Estimate KW - Ki-67 Antigen KW - Laryngeal Neoplasms KW - Male KW - Membrane Proteins KW - Middle Aged KW - Neoplasm Recurrence, Local KW - Phosphorylation KW - Predictive Value of Tests KW - Proportional Hazards Models KW - Retrospective Studies KW - Risk Factors KW - Squamous Cell Carcinoma of Head and Neck KW - Time Factors KW - Treatment Outcome KW - Tumor Suppressor Protein p53 TI - Phosphorylation of gH2AX as a novel prognostic biomarker for laryngoesophageal dysfunction-free survival. TY - research article VL - 7 ER -