RT Journal Article
T1 Hempseed (Cannabis sativa) protein hydrolysates: A valuable source of bioactive peptides with pleiotropic health-promoting effects
A1 Santos-Sanchez, Guillermo
A1 Isabel Alvarez-Lopez, Ana
A1 Ponce-Espana, Eduardo
A1 Carrillo-Vico, Antonio
A1 Bollati, Carlotta
A1 Bartolomei, Martina
A1 Lammi, Carmen
A1 Cruz-Chamorro, Ivan
K1 Bioactive peptide
K1 Antioxidant
K1 Inflammation
K1 Hypertension
K1 Hyperglycemia
K1 Hypercholesterolemia
K1 Angiotensin-converting enzyme
K1 Ace-inhibitory peptides
K1 Antioxidant properties
K1 In-vitro
K1 L.
K1 Cholesterol
K1 Identification
K1 Hypertension
K1 Mechanism
K1 Risk
AB Background: Recently, the study of hydrolysates from food proteins has been increasingly due to their wide range of biological activities. Hydrolysates contain peptides of 2-20 amino acids that are inactive within the sequence of the parent protein, but, once released after proteolytic processes, they exert numerous beneficial health effects. Hemp, the non-drug variety of Cannabis sativa, is known as an important source of bioactive peptides due to the high quality of hempseeds protein (20-25%) and well-balanced amino acid profile. For this reason, during the last decade, numerous investigations have searched to elucidate the beneficial effects on the health of these hempseed protein hydrolysates. Scope and approach: The aim of this review was to collect all the scientific evidence on the demonstrated beneficial effects of hempseed protein hydrolysates (HHs). Key findings and conclusions: HHs have showed to possess antioxidant, immunomodulatory, hypotensive, hypo-glycemic, and lipid-lowering capacities in vitro systems. All these effects have pointed out HHs as future ingredient for the development of functional foods or dietary supplements useful for the prevention of chronic diseases such as metabolic syndrome, diabetes or hypertension. However, few studies have evaluated the in vivo effects of HHs. For this reason, further studies carried out in animal models or human are necessary to better exploit the use of HHs for the development of new dietary supplements.
PB Elsevier science london
SN 0924-2244
YR 2022
FD 2022-08-03
LK http://hdl.handle.net/10668/22529
UL http://hdl.handle.net/10668/22529
LA en
DS RISalud
RD Apr 5, 2025