TY - JOUR AU - Seymour, John F AU - Döhner, Hartmut AU - Butrym, Aleksandra AU - Wierzbowska, Agnieszka AU - Selleslag, Dominik AU - Jang, Jun Ho AU - Kumar, Rajat AU - Cavenagh, James AU - Schuh, Andre C AU - Candoni, Anna AU - Recher, Christian AU - Sandhu, Irwindeep AU - Bernal-del-Castillo, Teresa AU - Al-Ali, Haifa Kathrin AU - Falantes, Jose AU - Stone, Richard M AU - Minden, Mark D AU - Weaver, Jerry AU - Songer, Steve AU - Beach, C L AU - Dombret, Herve PY - 2017 DO - 10.1186/s12885-017-3803-6 UR - http://hdl.handle.net/10668/11907 T2 - BMC cancer AB - Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to have poor-risk cytogenetics, leading to poor... LA - en PB - BioMed Central Ltd. KW - AML KW - AML-MRC KW - Acute myeloid leukaemia KW - Azacitidine KW - Induction chemotherapy KW - Low-dose cytarabine KW - Myelodysplasia-related changes KW - Response KW - Survival KW - Age Factors KW - Aged KW - Aged, 80 and over KW - Antimetabolites, Antineoplastic KW - Azacitidine KW - Cytarabine KW - Female KW - Humans KW - Kaplan-Meier Estimate KW - Leukemia, Myeloid, Acute KW - Male KW - Myelodysplastic Syndromes KW - Prognosis KW - Treatment Outcome TI - Azacitidine improves clinical outcomes in older patients with acute myeloid leukaemia with myelodysplasia-related changes compared with conventional care regimens. TY - research article VL - 17 ER -