TY - JOUR AU - Cariou, B AU - Leiter, L A AU - Müller-Wieland, D AU - Bigot, G AU - Colhoun, H M AU - Del Prato, S AU - Henry, R R AU - Tinahones, F J AU - Letierce, A AU - Aurand, L AU - Maroni, J AU - Ray, K K AU - Bujas-Bobanovic, M PY - 2017 DO - 10.1016/j.diabet.2017.01.004 UR - http://hdl.handle.net/10668/11012 T2 - Diabetes & metabolism AB - The coadministration of alirocumab, a PCSK9 inhibitor for treatment of hypercholesterolaemia, and insulin in diabetes mellitus (DM) requires further study. Described here is the rationale behind a phase-IIIb study designed to characterize the efficacy... LA - en KW - Alirocumab KW - Diabetes KW - Insulin KW - LDL-C KW - ODYSSEY KW - PCSK9 KW - Adolescent KW - Adult KW - Aged KW - Antibodies, Monoclonal KW - Antibodies, Monoclonal, Humanized KW - Cardiovascular Diseases KW - Diabetes Mellitus, Type 1 KW - Diabetes Mellitus, Type 2 KW - Double-Blind Method KW - Drug Interactions KW - Female KW - Humans KW - Hypercholesterolemia KW - Insulin KW - Male KW - Middle Aged KW - Research Design KW - Risk Factors KW - Young Adult TI - Efficacy and safety of alirocumab in insulin-treated patients with type 1 or type 2 diabetes and high cardiovascular risk: Rationale and design of the ODYSSEY DM-INSULIN trial. TY - research article VL - 43 ER -