RT Journal Article T1 Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain) A1 Casimiro-Soriguer, Carlos S. A1 Perez-Florido, Javier A1 Fernandez-Rueda, Jose L. A1 Pedrosa-Corral, Irene A1 Guillot-Sulay, Vicente A1 Lorusso, Nicola A1 Martinez-Gonzalez, Luis Javier A1 Navarro-Marí, Jose M. A1 Dopazo, Joaquin A1 Sanbonmatsu-Gámez, Sara K1 West Nile virus K1 Outbreak K1 Meningoencephalitis K1 Epidemiology K1 Phylogeny K1 Whole genome sequencing K1 Fiebre del Nilo occidental K1 Brotes de enfermedades K1 Meningoencefalitis K1 Epidemiología K1 Filogenia K1 Secuenciación completa del genoma AB During recent decades West Nile Virus (WNV) outbreaks have continuously occurred in the Mediterranean area. In August 2020 a new WNV outbreak affected 71 people with meningoencephalitis in Andalusia and six more cases were detected in Extremadura (south-west of Spain), causing a total of eight deaths. The whole genomes of four viruses were obtained and phylogenetically analyzed in the context of recent outbreaks. The Andalusian viral samples belonged to lineage 1 and were relatively similar to those of previous outbreaks which occurred in the Mediterranean region. Here we present a detailed analysis of the outbreak, including an extensive phylogenetic study. As part on this effort, we implemented a local Nextstrain server, which has become a constituent piece of regional epidemiological surveillance, wherein forthcoming genomes of environmental samples or, eventually, future outbreaks, will be included. PB MDPI AG YR 2021 FD 2021-05-05 LK http://hdl.handle.net/10668/3467 UL http://hdl.handle.net/10668/3467 LA en NO Casimiro-Soriguer CS, Perez-Florido J, Fernandez-Rueda JL, Pedrosa-Corral I, Guillot-Sulay V, Lorusso N, et al. Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain). Viruses. 2021; 13(5):836. DS RISalud RD Apr 9, 2025