RT Journal Article
T1 The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
A1 Jimeno, Sonia
A1 Balestra, Fernando R.
A1 Huertas, Pablo
K1 RNA modification
K1 DNA repair
K1 Homologous recombination
K1 DNA resection
K1 R-loop
K1 Procesamiento postranscripcional del ARN
K1 Reparación del ADN
K1 Recombinación homóloga
K1 Estructuras R-loop
K1 ADN
AB The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the survival and fitness of any living organism. Indeed, the repair of these lesions is a complicated affair, in which several pathways compete for the DNA ends in a complex balance. Thus, the fine-tuning of the DNA double-strand break repair pathway choice relies on the different regulatory layers that respond to environmental cues. Among those different tiers of regulation, RNA modifications have just emerged as a promising field.
PB Frontiers
YR 2021
FD 2021-04-29
LK http://hdl.handle.net/10668/4246
UL http://hdl.handle.net/10668/4246
LA en
NO Jimeno S, Balestra FR, Huertas P. The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair. Front Mol Biosci. 2021 Apr 29;8:664872
DS RISalud
RD Apr 8, 2025