TY - JOUR AU - Rojas-Torres, Marta AU - Jiménez-Palomares, Margarita AU - Martín-Ramírez, Javier AU - Beltrán-Camacho, Lucía AU - Sánchez-Gomar, Ismael AU - Eslava-Alcon, Sara AU - Rosal-Vela, Antonio AU - Gavaldá, Sandra AU - Durán-Ruiz, M. Carmen PY - 2020 DO - 10.3389/fcell.2020.602837 UR - http://hdl.handle.net/10668/3793 T2 - Frontiers in Cell and Developmental Biology AB - Background: Bone Marrow Mononuclear Cells (BM-MNC) constitute a promising alternative for the treatment of Chronic Limb-Threatening ischemia (CLTI), a disease characterized by extensive blockade of peripheral arteries, clinically presenting as... LA - en PB - Frontiers KW - Chronic limb-threatening ischemia KW - Critical limb ischemia KW - Stem cell therapy KW - Revascularization KW - Angiogenesis KW - BM-MNC KW - Bio-distribution assay KW - Isquemia crónica que amenaza las extremidades KW - Tratamiento Basado en trasplante de células y tejidos KW - Células madre KW - Animales KW - Células de la médula ósea KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Cell- and Tissue-Based Therapy KW - Medical Subject Headings::Anatomy::Cells::Stem Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Anatomy::Cells::Bone Marrow Cells KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Animal::Disease Models, Animal KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal... KW - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Bone Marrow KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Cytological Techniques::Cell Tracking KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Orthopedic Procedures::Amputation KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Ulcer KW - Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Hemodynamics::Hemorheology::Blood Flow Velocity KW - Medical Subject Headings::Persons::Persons::Patients TI - REX-001, a BM-MNC Enriched Solution, Induces Revascularization of Ischemic Tissues in a Murine Model of Chronic Limb-Threatening Ischemia TY - research article ER -