TY  - JOUR
AU  - Bravo-Caparros, Inmaculada
AU  - Perazzoli, Gloria
AU  - Yeste, Sandra
AU  - Cikes, Domagoj
AU  - Baeyens, Jose Manuel
AU  - Cobos, Enrique Jose
AU  - Nieto, Francisco Rafael
PY  - 2019
DO  - 10.3389/fphar.2019.00613
SN  - 1663-9812
UR  - http://hdl.handle.net/10668/14207
T2  - Frontiers in pharmacology
AB  - Sigma-1 (σ1) receptor antagonists are promising tools for neuropathic pain treatment, but it is unknown whether σ1 receptor inhibition ameliorates the neuropathic signs induced by nerve transection, in which the pathophysiological mechanisms and...
LA  - en
PB  - Frontiers Research Foundation
KW  - S1RA
KW  - cold allodynia
KW  - endogenous opioid system
KW  - heat hyperalgesia
KW  - mechanical allodynia
KW  - neuropathic pain
KW  - sigma-1 receptors
KW  - spared nerve injury
KW  - Mice
KW  - Animals
KW  - Hyperalgesia
KW  - Analgesics, Opioid
KW  - Narcotic Antagonists
KW  - 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate
KW  - Acetone
KW  - N-methylnaloxone
KW  - Mice, Knockout
KW  - Hot Temperature
KW  - Neuralgia
KW  - Naloxone
KW  - Peripheral Nerves
KW  - Brain
TI  - Sigma-1 Receptor Inhibition Reduces Neuropathic Pain Induced by Partial Sciatic Nerve Transection in Mice by Opioid-Dependent and -Independent Mechanisms.
TY  - research article
VL  - 10
ER  -