RT Journal Article T1 Cambios en la epidemiología y en la práctica clínica dela alergia mediada por IgE en pediatría T2 Changes in epidemiology and clinical practice in IgE-mediated allergy in children A1 Escarrer-Jaume, Mercedes A1 Julia-Benito, Juan Carlos A1 Quevedo-Teruel, Sergio A1 Prieto-del-Prado, Ana A1 Sandoval-Ruballos, Monica A1 Quesada-Sequeira, Fabriella A1 Alvaro-Lozano, Montserrat K1 Pediatric K1 Changes K1 Allergy K1 Epidemiology K1 Allergen K1 Diagnosis K1 Immunotherapy K1 Biologics K1 Pediátrica K1 Cambios K1 Alergia K1 Epidemiología K1 Alérgeno K1 Diagnóstico K1 Inmunoterapia K1 Biológicos AB In the last decades, allergic diseases have increased exponentially and although pediatric asthma prevalence is stabilizing, in Spain is estimated around 10%. Not the same with food allergy and anaphylaxis which are clearly increasing, becoming a public health problem of the first magnitude. Considering epidemiological trends, the European Academy of Allergy and Clinical Immunology (EAACI) estimates that in less than 15 years more than half of European population will suffer from some type of allergy.The advances in diagnostic methods in food allergy, especially component resolved diagnosis, allow us to know the patient's sensitization profile and explain the possible cross reactivity, anticipate potential risk of food transgressions, and prescribe the correct avoidance diet in each patient. Thus, the development of molecular biology and nanotechnology have led to the appearance of new technologies (microarrays) which facilitate the study, specially of the polysensitized patients, allowing allergen immunotherapy (AIT) to be more personalized. The latest advances in the use of biologics are having an impact, not only in disease evolution, but also in patients quality of life. (C) 2021 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U. PB Elsevier SN 1695-4033 YR 2021 FD 2021-06-10 LK http://hdl.handle.net/10668/18699 UL http://hdl.handle.net/10668/18699 LA es NO Escarrer-Jaume, M., Juliá-Benito, J. C., Quevedo-Teruel, S., Del-Prado, A. P., Sandoval-Ruballos, M., Quesada-Sequeira, F., et al. Cambios en la epidemiología y en la práctica clínica de la alergia mediada por IgE en pediatría. Anales de Pediatría, 95(1), 56.e1-56.e8 DS RISalud RD Apr 12, 2025