TY  - JOUR
AU  - Toro, Ayelén Rayen
AU  - Maymó, Julieta Lorena
AU  - Ibarbalz, Federico Matías
AU  - Pérez Pérez, Antonio
AU  - Maskin, Bernardo
AU  - Faletti, Alicia Graciela
AU  - Sánchez Margalet, Víctor
AU  - Varone, Cecilia Laura
PY  - 2014
DO  - 10.1371/journal.pone.0099187
UR  - http://hdl.handle.net/10668/1862
T2  - PloS one
AB  - Leptin, a peripheral signal synthetized by the adipocyte to regulate energy metabolism, can also be produced by placenta, where it may work as an autocrine hormone. We have previously demonstrated that leptin promotes proliferation and survival of...
LA  - en
PB  - Public Library of Science
KW  - Leptina
KW  - Placenta
KW  - Coriocarcinoma
KW  - Apoptosis
KW  - Embarazo
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Proto-Oncogene Proteins c-bcl-2::BH3 Interacting Domain Death Agonist Protein
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Adipokines::Leptin
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Phosphorylation
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Phosphoamino Acids::Phosphoserine
KW  - Medical Subject Headings::Anatomy::Embryonic Structures::Placenta
KW  - Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Infection::Pregnancy Complications, Infectious
KW  - Medical Subject Headings::Anatomy::Cells::Endocrine Cells::Trophoblasts
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Tumor Suppressor Protein p53
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Proto-Oncogene Proteins c-bcl-2::bcl-2-Associated X Protein
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis
TI  - Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation.
TY  - research article
ER  -