RT Journal Article T1 Real-life effect of a microcrystalline tyrosine adjuvanted mite immunotherapy in patients with allergic rhinitis. A1 Roger, Albert A1 Malet, Alfons A1 Moreno, Victoria A1 Parra, Antonio A1 Gutiérrez, Diego A1 Lleonart, Ramón A1 Moreno, Francisco A1 Valero, Antonio A1 Navarro, Begoña A1 Hinojosa, Belén A1 Justicia, José L K1 Dermatophagoides pteronyssinus K1 adjuvants K1 allergic rhinitis K1 effectiveness K1 house dust mites K1 real-life clinical practice K1 safety K1 subcutaneous allergen immunotherapy AB Aim: Evaluate the effectiveness and safety of immunotherapy with Acarovac Plus® in a 1-year prospective multicentered real-life study. Methods: A total of 118 adults with allergic rhinitis sensitized to Dermatophagoides received subcutaneous immunotherapy with Acarovac Plus. Treatment outcomes were evaluated at baseline, 6 months and 1 year after treatment initiation. Primary end point was the evolution of the combined symptom and medication score. Secondary end points included other effectiveness outcomes and measurement of product tolerability. Results: Acarovac Plus induced significant improvements in primary and secondary end points after 6 months compared with baseline. These differences persisted after 1 year of treatment (p YR 2020 FD 2020-01-08 LK http://hdl.handle.net/10668/14927 UL http://hdl.handle.net/10668/14927 LA en DS RISalud RD Apr 10, 2025