%0 Journal Article
%A Roger, Albert
%A Malet, Alfons
%A Moreno, Victoria
%A Parra, Antonio
%A Gutiérrez, Diego
%A Lleonart, Ramón
%A Moreno, Francisco
%A Valero, Antonio
%A Navarro, Begoña
%A Hinojosa, Belén
%A Justicia, José L
%T Real-life effect of a microcrystalline tyrosine adjuvanted mite immunotherapy in patients with allergic rhinitis.
%D 2020
%U http://hdl.handle.net/10668/14927
%X Aim: Evaluate the effectiveness and safety of immunotherapy with Acarovac Plus® in a 1-year prospective multicentered real-life study. Methods: A total of 118 adults with allergic rhinitis sensitized to Dermatophagoides received subcutaneous immunotherapy with Acarovac Plus. Treatment outcomes were evaluated at baseline, 6 months and 1 year after treatment initiation. Primary end point was the evolution of the combined symptom and medication score. Secondary end points included other effectiveness outcomes and measurement of product tolerability. Results: Acarovac Plus induced significant improvements in primary and secondary end points after 6 months compared with baseline. These differences persisted after 1 year of treatment (p
%K Dermatophagoides pteronyssinus
%K adjuvants
%K allergic rhinitis
%K effectiveness
%K house dust mites
%K real-life clinical practice
%K safety
%K subcutaneous allergen immunotherapy
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