TY - JOUR AU - Montilla-García, Ángeles AU - Tejada, Miguel Á AU - Ruiz-Cantero, M Carmen AU - Bravo-Caparrós, Inmaculada AU - Yeste, Sandra AU - Zamanillo, Daniel AU - Cobos, Enrique J PY - 2019 DO - 10.3389/fphar.2019.00136 SN - 1663-9812 UR - https://hdl.handle.net/10668/26164 T2 - Frontiers in pharmacology AB - Sigma-1 receptor antagonism increases the effects of morphine on nociceptive pain, even in morphine-tolerant animals. However, it is unknown whether these receptors are able to modulate morphine antinociception and tolerance during inflammatory pain.... LA - en KW - analgesia KW - grip strength KW - joint inflammation KW - morphine KW - pain KW - sigma-1 receptors KW - tolerance KW - von Frey threshold TI - Modulation by Sigma-1 Receptor of Morphine Analgesia and Tolerance: Nociceptive Pain, Tactile Allodynia and Grip Strength Deficits During Joint Inflammation. TY - research article VL - 10 ER -