TY - JOUR AU - Nedeljkovic, Ivana AU - Carnero-Montoro, Elena AU - Lahousse, Lies AU - van der Plaat, Diana A AU - de Jong, Kim AU - Vonk, Judith M AU - van Diemen, Cleo C AU - Faiz, Alen AU - van den Berge, Maarten AU - Obeidat, Ma'en AU - Bossé, Yohan AU - Nickle, David C AU - Consortium, Bios AU - Uitterlinden, Andre G AU - van Meurs, Joyce J B AU - Stricker, Bruno C H AU - Brusselle, Guy G AU - Postma, Dirkje S AU - Boezen, H Marike AU - van Duijn, Cornelia M AU - Amin, Najaf PY - 2018 DO - 10.1038/s41431-017-0089-8 UR - http://hdl.handle.net/10668/12105 T2 - European journal of human genetics : EJHG AB - Chronic obstructive pulmonary disease (COPD) is a major health burden in adults and cigarette smoking is considered the most important environmental risk factor of COPD. Chromosome 15q25.1 locus is associated with both COPD and smoking. Our study aims... LA - en KW - Aged KW - Chromosomes, Human, Pair 15 KW - Cigarette Smoking KW - DNA Methylation KW - Female KW - Gene Expression Regulation KW - Genetic Association Studies KW - Genetic Predisposition to Disease KW - Humans KW - Iron Regulatory Protein 2 KW - Male KW - Middle Aged KW - Proteasome Endopeptidase Complex KW - Pulmonary Disease, Chronic Obstructive KW - Quantitative Trait Loci KW - Receptors, Nicotinic KW - Risk Factors TI - Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics. TY - research article VL - 26 ER -