TY - JOUR AU - Cañas, Juan Carlos AU - García-Rubio, María Luisa AU - García, Alicia AU - Antequera, Francisco AU - Gómez-González, Belén AU - Aguilera, Andrés PY - 2022 DO - 10.1093/genetics/iyac108 UR - http://hdl.handle.net/10668/19782 T2 - Genetics AB - The stability of the genome is occasionally challenged by the formation of DNA-RNA hybrids and R-loops, which can be influenced by the chromatin context. This is mainly due to the fact that DNA-RNA hybrids hamper the progression of replication forks,... LA - en KW - DNA–RNA hybrids KW - R-loops KW - genetic instability KW - histone acetylation KW - sister-chromatid recombination KW - Acetylation KW - Chromatin KW - DNA Replication KW - Genomic Instability KW - Histone Acetyltransferases KW - Homeostasis KW - R-Loop Structures KW - RNA KW - Saccharomyces cerevisiae KW - Saccharomyces cerevisiae Proteins TI - A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability. TY - research article VL - 222 ER -