RT Journal Article
T1 Incidence, Outcomes and Sex-Related Disparities in Pneumonia: A Matched-Pair Analysis with Data from Spanish Hospitals (2016-2019)
A1 de Miguel-Yanes, Jose M.
A1 Lopez-de-Andres, Ana
A1 Jiménez-Garcia, Rodrigo
A1 Hernandez-Barrera, Valentin
A1 de Miguel-Diez, Javier
A1 Carabantes-Alarcon, David
A1 Perez-Farinos, Napoleon
A1 Wärnberg, Julia
K1 Community-acquired pneumonia
K1 Hospital-acquired pneumonia
K1 Ventilator-associated pneumonia
K1 Gender
K1 Sex differences
K1 In-hospital mortality
K1 Neumonía asociada al cuidado de la salud
K1 Neumonía asociada al ventilador
K1 Género y salud
K1 Características sexuales
K1 Mortalidad hospitalaria
AB Background: the purpose of this study is to analyze the incidence and in-hospital mortality (IHM) of community-acquired pneumonia (CAP) needing hospital admission and hospital-acquired pneumonia (HAP) in Spain (2016-2019). Methods: using the Spanish Register of Specialized Care-Basic Minimum Database, we estimated the incidence of CAP and HAP. We matched each woman with a man with an identical age, according to comorbidities. Results: we analyzed 518,838 cases of CAP and 38,705 cases of HAP, and 5192 ventilator-associated HAPs (13.4%). The incidence of CAP increased over time in both men (from 384.5 to 449.8 cases/105 population) and women (from 244.9 to 301.2 cases/105 population). Men showed a 47% higher adjusted incidence of CAP than women. The incidence of HAP increased over time in both men (from 302.3 to 342.2 cases/105 population) and women (from 139.2 to 167.6 cases/105 population). Men showed a 98% higher adjusted incidence of HAP than women. IHM was higher in men admitted for CAP than in women (12.9% vs. 12.2%; p < 0.001), but not in men who developed HAP (28.9% vs. 28.0%; p = 0.107). Men admitted for CAP (OR: 1.13; 95% CI: 1.10-1.15) and men who developed HAP (OR: 1.05; 95% CI: 1.01-1.10) had higher IHM than women. Conclusions: men had higher incidence rates of CAP and HAP than women. Men admitted for CAP and men who developed HAP had higher IHM than women.
PB MDPI
YR 2021
FD 2021-09-23
LK http://hdl.handle.net/10668/3902
UL http://hdl.handle.net/10668/3902
LA en
NO de Miguel-Yanes JM, Lopez-de-Andres A, Jiménez-Garcia R, Hernandez-Barrera V, de Miguel-Diez J, Carabantes-Alarcon D, et al. Incidence, Outcomes and Sex-Related Disparities in Pneumonia: A Matched-Pair Analysis with Data from Spanish Hospitals (2016-2019). J Clin Med. 2021 Sep 23;10(19):4339
DS RISalud
RD Apr 14, 2025