%0 Journal Article
%A de Miguel-Yanes, Jose M.
%A Lopez-de-Andres, Ana
%A Jiménez-Garcia, Rodrigo
%A Hernandez-Barrera, Valentin
%A de Miguel-Diez, Javier
%A Carabantes-Alarcon, David
%A Perez-Farinos, Napoleon
%A Wärnberg, Julia
%T Incidence, Outcomes and Sex-Related Disparities in Pneumonia: A Matched-Pair Analysis with Data from Spanish Hospitals (2016-2019)
%D 2021
%U http://hdl.handle.net/10668/3902
%X Background: the purpose of this study is to analyze the incidence and in-hospital mortality (IHM) of community-acquired pneumonia (CAP) needing hospital admission and hospital-acquired pneumonia (HAP) in Spain (2016-2019). Methods: using the Spanish Register of Specialized Care-Basic Minimum Database, we estimated the incidence of CAP and HAP. We matched each woman with a man with an identical age, according to comorbidities. Results: we analyzed 518,838 cases of CAP and 38,705 cases of HAP, and 5192 ventilator-associated HAPs (13.4%). The incidence of CAP increased over time in both men (from 384.5 to 449.8 cases/105 population) and women (from 244.9 to 301.2 cases/105 population). Men showed a 47% higher adjusted incidence of CAP than women. The incidence of HAP increased over time in both men (from 302.3 to 342.2 cases/105 population) and women (from 139.2 to 167.6 cases/105 population). Men showed a 98% higher adjusted incidence of HAP than women. IHM was higher in men admitted for CAP than in women (12.9% vs. 12.2%; p < 0.001), but not in men who developed HAP (28.9% vs. 28.0%; p = 0.107). Men admitted for CAP (OR: 1.13; 95% CI: 1.10-1.15) and men who developed HAP (OR: 1.05; 95% CI: 1.01-1.10) had higher IHM than women. Conclusions: men had higher incidence rates of CAP and HAP than women. Men admitted for CAP and men who developed HAP had higher IHM than women.
%K Community-acquired pneumonia
%K Hospital-acquired pneumonia
%K Ventilator-associated pneumonia
%K Gender
%K Sex differences
%K In-hospital mortality
%K Neumonía asociada al cuidado de la salud
%K Neumonía asociada al ventilador
%K Género y salud
%K Características sexuales
%K Mortalidad hospitalaria
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