%0 Journal Article
%A Santos Garcia, D.
%A De Deus Fonticoba, T.
%A Paz Gonzalez, J. M.
%A Cores Bartolome, C.
%A Valdes Aymerich, L.
%A Munoz Enriquez, J. G.
%A Suarez, E.
%A Jesus, S.
%A Aguilar, M.
%A Pastor, P.
%A Planellas, L. L.
%A Cosgaya, M.
%A Garcia Caldentey, J.
%A Caballol, N.
%A Legarda, I.
%A Hernandez Vara, J.
%A Cabo, I.
%A Lopez Manzanares, L.
%A Gonzalez Aramburu, I.
%A Avila Rivera, M. A.
%A Catalan, M. J.
%A Nogueira, V.
%A Puente, V.
%A Garcia Moreno, J. M.
%A Borrue, C.
%A Solano Vila, B.
%A Alvarez Sauco, M.
%A Vela, L.
%A Escalante, S.
%A Cubo, E.
%A Carrillo Padilla, F.
%A Martinez Castrillo, J. C.
%A Sanchez Alonso, P.
%A Alonso Losada, M. G.
%A Lopez Ariztegui, N.
%A Gaston, I.
%A Kulisevsky, J.
%A Blazquez Estrada, M.
%A Seijo, M.
%A Ruiz Martinez, J.
%A Valero, C.
%A Kurtis, M.
%A de Fabregues, O.
%A Gonzalez Ardura, J.
%A Ordas, C.
%A Lopez Diaz, L.
%A Mir, P.
%A Martinez-Martin, P.
%A COPPADIS Study Grp
%T Staging Parkinson's Disease Combining Motor and Nonmotor Symptoms Correlates with Disability and Quality of Life
%D 2021
%@ 2090-8083
%U http://hdl.handle.net/10668/19080
%X Introduction. In a degenerative disorder such as Parkinson's disease (PD), it is important to establish clinical stages that allow to know the course of the disease. Our aim was to analyze whether a scale combining Hoehn and Yahr's motor stage (H&Y) and the nonmotor symptoms burden (NMSB) (assessed by the nonmotor symptoms scale (NMSS)) provides information about the disability and the patient's quality of life (QoL) with regard to a defined clinical stage. Materials and Methods. Cross-sectional study in which 603 PD patients from the COPPADIS cohort were classified according to H&Y (1, stage I; 2, stage II; 3, stage III; 4, stage IV/V) and NMSB (A: NMSS=0-20; B: NMSS=21-40; C: NMSS=41-70; D: NMSS >= 71) in 16 stages (HY.NMSB, from 1A to 4D). QoL was assessed with the PDQ-39SI, PQ-10, and EUROHIS-QOL8 and disability with the Schwab&England ADL (Activities of Daily Living) scale. Results. A worse QoL and greater disability were observed at a higher stage of H&Y and NMSB (p= 71) in 16 stages (HY.NMSB, from 1A to 4D). QoL was assessed with the PDQ-39SI, PQ-10, and EUROHIS-QOL8 and disability with the Schwab&England ADL (Activities of Daily Living) scale. Results. A worse QoL and greater disability were observed at a higher stage of H&Y and NMSB (p
%K Scale
%K Questionnaire
%K Subtypes
%K Impact
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