TY - JOUR AU - López-Saavedra, Ana AU - Gómez-Cabello, Daniel AU - Domínguez-Sánchez, María Salud AU - Mejías-Navarro, Fernando AU - Fernández-Ávila, María Jesús AU - Dinant, Christoffel AU - Martínez-Macías, María Isabel AU - Bartek, Jiri AU - Huertas, Pablo PY - 2016 DO - 10.1038/ncomms12364 UR - http://hdl.handle.net/10668/10347 T2 - Nature communications AB - There are two major and alternative pathways to repair DNA double-strand breaks: non-homologous end-joining and homologous recombination. Here we identify and characterize novel factors involved in choosing between these pathways; in this study we... LA - en KW - Adaptor Proteins, Signal Transducing KW - Carrier Proteins KW - Cell Line, Tumor KW - Chromatin KW - DNA Damage KW - DNA End-Joining Repair KW - Endodeoxyribonucleases KW - Gene Regulatory Networks KW - Genome, Human KW - Humans KW - Models, Biological KW - Nuclear Proteins KW - Protein Binding KW - Recombinational DNA Repair TI - A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection. TY - research article VL - 7 ER -