RT Journal Article
T1 Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms.
A1 Toledano, Juan M
A1 Moreno-Fernandez, Jorge
A1 Puche-Juarez, Maria
A1 Ochoa, Julio J
A1 Diaz-Castro, Javier
K1 COVID-19
K1 SARS-CoV-2
K1 immunity
K1 inflammation
K1 nutrients
K1 oxidative stress
K1 vitamins
AB Since the appearance of the coronavirus disease 2019 (COVID-19) and its announcement as a global pandemic, the search for prophylactic and therapeutic options have become a priority for governments and the scientific community. The approval of several vaccines against SARS-CoV-2 is being crucial to overcome this situation, although the victory will not be achieved while the whole population worldwide is not protected against the virus. This is why alternatives should be studied in order to successfully support the immune system before and during a possible infection. An optimal inflammatory and oxidative stress status depends on an adequate diet. Poor levels of several nutrients could be related to an impaired immune response and, therefore, an increased susceptibility to infection and serious outcomes. Vitamins exert a number of anti-microbial, immunomodulatory, anti-inflammatory, and antioxidant activities, which can be of use to fight against this and several other diseases (especially vitamin D and C). Even though they cannot be considered as a definitive therapeutic option, in part owing to the lack of solid conclusions from well-designed clinical trials, currently available evidence from similar respiratory diseases may indicate that it would be rational to deeply explore the use of vitamins during this global pandemic.
PB MDPI AG
SN 2076-3921
YR 2021
FD 2021-12-20
LK http://hdl.handle.net/10668/20767
UL http://hdl.handle.net/10668/20767
LA en
NO Toledano JM, Moreno-Fernandez J, Puche-Juarez M, Ochoa JJ, Diaz-Castro J. Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms. Antioxidants (Basel). 2021 Dec 21;11(1):5.
DS RISalud
RD Apr 12, 2025