TY - JOUR AU - Rizvi, Naiyer A AU - Cho, Byoung Chul AU - Reinmuth, Niels AU - Lee, Ki Hyeong AU - Luft, Alexander AU - Ahn, Myung-Ju AU - van-den-Heuvel, Michel M AU - Cobo, Manuel AU - Vicente, David AU - Smolin, Alexey AU - Moiseyenko, Vladimir AU - Antonia, Scott J AU - Le-Moulec, Sylvestre AU - Robinet, Gilles AU - Natale, Ronald AU - Schneider, Jeffrey AU - Shepherd, Frances A AU - Geater, Sarayut Lucien AU - Garon, Edward B AU - Kim, Edward S AU - Goldberg, Sarah B AU - Nakagawa, Kazuhiko AU - Raja, Rajiv AU - Higgs, Brandon W AU - Boothman, Anne-Marie AU - Zhao, Luping AU - Scheuring, Urban AU - Stockman, Paul K AU - Chand, Vikram K AU - Peters, Solange PY - 2020 DO - 10.1001/jamaoncol.2020.0237 UR - http://hdl.handle.net/10668/15348 T2 - JAMA oncology AB - Checkpoint inhibitors targeting programmed cell death 1 or its ligand (PD-L1) as monotherapies or in combination with anti-cytotoxic T-lymphocyte-associated antigen 4 have shown clinical activity in patients with metastatic non-small cell lung cancer.... LA - en PB - American Medical Association KW - Antibodies, Monoclonal KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Agents, Immunological KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Combined Chemotherapy Protocols KW - Carcinoma, Non-Small-Cell Lung KW - Female KW - Humans KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Neoplasm Metastasis TI - Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non-Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial. TY - research article VL - 6 ER -