TY - JOUR AU - Palomino-Morales, Rogelio J AU - Vazquez-Rodriguez, Tomas R AU - Torres, Orlando AU - Morado, Inmaculada C AU - Castañeda, Santos AU - Miranda-Filloy, Jose A AU - Callejas-Rubio, Jose L AU - Fernandez-Gutierrez, Benjamin AU - Gonzalez-Gay, Miguel A AU - Martin, Javier PY - 2010 DO - 10.1186/ar2962 SN - 1478-6354 UR - http://hdl.handle.net/10668/390 T2 - Arthritis Research & Therapy AB - INTRODUCCIÓN: El objetivo fue investigar la posible implicación de los polimorfismos de promotor del gen IL18 en la susceptibilidad a la arteritis de células gigantes (ACG). MÉTODOS: En total, 212 pacientes con diagnóstico de ACG probada por biopsia... AB - INTRODUCTION: The objective was to investigate the potential implication of the IL18 gene promoter polymorphisms in the susceptibility to giant-cell arteritis GCA). METHODS: In total, 212 patients diagnosed with biopsy-proven GCA were included in this... LA - en PB - BioMed Central KW - Biopsia KW - Quimioterapia Combinada KW - Predisposición Genética a la Enfermedad KW - Genotipo KW - Arteritis de Células Gigantes KW - Interleucina-18 KW - Desequilibrio de Ligamiento KW - Metilprednisolona KW - Polimorfismo Genético KW - Prednisona KW - Receptor Toll-Like 4 KW - Humanos KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Biopsy KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Therapy, Combination KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases::Autoimmune Diseases of the Nervous System::Vasculitis, Central Nervous System::Giant Cell Arteritis KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-18 KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Linkage::Linkage Disequilibrium KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Steroids::Pregnanes::Pregnadienes::Pregnadienetriols::Prednisolone::Methylprednisolone KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Steroids::Pregnanes::Pregnadienes::Pregnadienediols::Prednisone KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Pattern Recognition::Toll-Like Receptors::Toll-Like Receptor 4 KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans TI - Association between IL-18 gene polymorphisms and biopsy-proven giant cell TY - research article ER -