TY  - JOUR
AU  - Teruel, María
AU  - Barturen, Guillermo
AU  - Martínez-Bueno, Manuel
AU  - Castellini-Pérez, Olivia
AU  - Barroso-Gil, Miguel
AU  - Povedano, Elena
AU  - Kerick, Martin
AU  - Català-Moll, Francesc
AU  - Makowska, Zuzanna
AU  - Buttgereit, Anne
AU  - Pers, Jacques-Olivier
AU  - Marañón, Concepción
AU  - Ballestar, Esteban
AU  - Martin, Javier
AU  - Carnero-Montoro, Elena
AU  - Alarcón-Riquelme, Marta E.
PY  - 2021
DO  - 10.1038/s41598-021-01324-0
UR  - http://hdl.handle.net/10668/4558
T2  - Scientific Reports
AB  - Primary Sjögren’s syndrome (SS) is a systemic autoimmune disease characterized by lymphocytic infiltration and damage of exocrine salivary and lacrimal glands. The etiology of SS is complex with environmental triggers and genetic factors involved. By...
LA  - en
PB  - Springer Nature
KW  - Autoantibodies
KW  - Epigenetic
KW  - Autoimmune diseases
KW  - Gene expression
KW  - Sjogren's syndrome
KW  - Genetic variation
KW  - Autoanticuerpos
KW  - Epigenómica
KW  - Enfermedades autoinmunes
KW  - Expresión génica
KW  - Síndrome de Sjögren
KW  - Variación genética
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::DNA Methylation
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Histocompatibility Antigens::HLA Antigens
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Interferons
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases::Arthritis, Rheumatoid::Sjogren's Syndrome
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics::Epigenomics
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic
KW  - Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases
TI  - Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature
TY  - research article
ER  -