TY  - JOUR
AU  - Chen, Xuyong
AU  - Sunkel, Benjamin
AU  - Wang, Meng
AU  - Kang, Siwen
AU  - Wang, Tingting
AU  - Gnanaprakasam, J N Rashida
AU  - Liu, Lingling
AU  - Cassel, Teresa A
AU  - Scott, David A
AU  - Muñoz-Cabello, Ana M
AU  - Lopez-Barneo, Jose
AU  - Yang, Jun
AU  - Lane, Andrew N
AU  - Xin, Gang
AU  - Stanton, Benjamin Z
AU  - Fan, Teresa W-M
AU  - Wang, Ruoning
PY  - 2022
DO  - 10.1126/sciimmunol.abm8161
UR  - http://hdl.handle.net/10668/20029
T2  - Science immunology
AB  - Effective T cell-mediated immune responses require the proper allocation of metabolic resources to sustain growth, proliferation, and cytokine production. Epigenetic control of the genome also governs T cell transcriptome and T cell lineage commitment...
LA  - en
KW  - Cell Proliferation
KW  - Chromatin
KW  - Electron Transport Complex II
KW  - Epigenesis, Genetic
KW  - Humans
KW  - Inflammation
KW  - Ketoglutaric Acids
KW  - Metabolism, Inborn Errors
KW  - Mitochondrial Diseases
KW  - Nucleosides
KW  - Succinate Dehydrogenase
KW  - Succinates
TI  - Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation.
TY  - research article
VL  - 7
ER  -