TY - JOUR AU - Díez-Quijada, Leticia AU - Medrano-Padial, Concepción AU - Llana-Ruiz-Cabello, María AU - Catunescu, Giorgiana M. AU - Moyano, Rosario AU - Risalde, Maria A. AU - Cameán, Ana M. AU - Jos, Ángeles PY - 2020 DO - 10.3390/toxins12060348 UR - http://hdl.handle.net/10668/3743 T2 - Toxins AB - Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and food. CYN/MC-LR mixtures previously investigated in vitro showed an induction of micronucleus (MN) formation only in the presence of... LA - en PB - MDPI KW - In vivo KW - Genotoxicity KW - Cylindrospermopsin KW - Microcystin-LR KW - Micronucleus KW - Comet assay KW - Enzyme-modified comet assay KW - Rats KW - Genotoxicidad KW - Cianotoxinas KW - Pruebas de micronúcleos KW - Ensayo cometa KW - Ratas KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Alkaloids KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Electrophoresis::Electrophoresis, Agar Gel::Comet Assay KW - Medical Subject Headings::Diseases::Digestive System Diseases::Liver Diseases::Fatty Liver KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Upper Gastrointestinal Tract::Stomach::Gastric Mucosa KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Hepatocytes KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Toxins, Biological::Marine Toxins KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Macrocyclic Compounds::Peptides, Cyclic::Microcystins KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Micronuclei, Chromosome-Defective KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Mutagenicity Tests::Micronucleus Tests KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Necrosis KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Wistar TI - Cylindrospermopsin-Microcystin-LR Combinations May Induce Genotoxic and Histopathological Damage in Rats TY - research article ER -