RT Journal Article
T1 Survival of patients >= 70 years with advanced chronic kidney disease: Dialysis vs. conservative care
A1 Martinez Echevers, Yeleine
A1 Toapanta Gaibor, Nestor Gabriel
A1 Nava Perez, Nathasha
A1 Barbosa Martin, Francisco
A1 Montes Delgado, Rafael
A1 Guerrero Riscos, Maria Angeles
K1 Advanced chronic kidney disease
K1 Elderly
K1 Survival
K1 Conservative care
K1 Frail patient
K1 Elderly-patients
K1 Population
K1 Prevention
K1 Management
K1 Initiation
K1 Outcomes
K1 Stage
AB Introduction: The number of elderly patients with advanced chronic kidney disease (ACKD) has increased in recent years, and the best therapeutic approach has not been determined due to a lack of evidence.Objectives: To observe the progression of elderly patients with ACKD (stages 4 and 5) and to compare the survival of stage 5 CKD patients with and without dialysis treatment.Material and methods: All patients >= 70 years who began ACKD follow-up from 01/01/2007 to 31/12/2008 were included, and their progression was observed until 31/12/2013. Demographic data, the Charlson comorbidity index, history of ischaemic heart disease (IHD) and diabetes mellitus (DM) were assessed.Results: A total of 314 patients >= 70 years with stages 4 and 5 CKD were studied. Of these patients, 162 patients had stage 5 CKD at the beginning of follow-up or progressed to stage 5 during the study, and 69 of these patients were treated with dialysis. In the stage 5 group: median age was 77 years (74-81); 48% had IHD; 50% had DM, Charlson 7 (6-9). Kaplan-Meier survival analysis: >= 70 years (93 vs. 69 patients with dialysis, log rank: 15 P= 70 years who began ACKD follow-up from 01/01/2007 to 31/12/2008 were included, and their progression was observed until 31/12/2013. Demographic data, the Charlson comorbidity index, history of ischaemic heart disease (IHD) and diabetes mellitus (DM) were assessed.Results: A total of 314 patients >= 70 years with stages 4 and 5 CKD were studied. Of these patients, 162 patients had stage 5 CKD at the beginning of follow-up or progressed to stage 5 during the study, and 69 of these patients were treated with dialysis. In the stage 5 group: median age was 77 years (74-81); 48% had IHD; 50% had DM, Charlson 7 (6-9). Kaplan-Meier survival analysis: >= 70 years (93 vs. 69 patients with dialysis, log rank: 15 P= 70 years with stages 4 and 5 CKD were studied. Of these patients, 162 patients had stage 5 CKD at the beginning of follow-up or progressed to stage 5 during the study, and 69 of these patients were treated with dialysis. In the stage 5 group: median age was 77 years (74-81); 48% had IHD; 50% had DM, Charlson 7 (6-9). Kaplan-Meier survival analysis: >= 70 years (93 vs. 69 patients with dialysis, log rank: 15 P= 70 years (93 vs. 69 patients with dialysis, log rank: 15 P= 75 years (74 vs. 46 patients with dialysis, log rank: 8.9 P=.003); patients >= 80 (40 vs. 15 patients with dialysis) and p=0,2. Patients receiving dialysis were younger, with a lower Charlson comorbidity index and shorter follow-up time.Conclusions: Our study shows that dialysis treatment improves survival, although this benefit is lost in patients >= 80 years. (C) 2016 Sociedad Espanola de Nefrologia. Published by Elsevier Espana, S.L.U.
PB Soc espanola nefrologia dr rafael matesanz
SN 0211-6995
YR 2016
FD 2016-05-01
LK http://hdl.handle.net/10668/18840
UL http://hdl.handle.net/10668/18840
LA es
DS RISalud
RD Apr 7, 2025