RT Journal Article
T1 Adverse Health Effects in Women Farmers Indirectly Exposed to Pesticides.
A1 Martin-Reina, Jose
A1 Casanova, Alfredo G
A1 Dahiri, Bouchra
A1 Fernández, Isaías
A1 Fernández-Palacín, Ana
A1 Bautista, Juan
A1 Morales, Ana I
A1 Moreno, Isabel
K1 cholinesterase
K1 early kidney damage
K1 oxidative stress
K1 pesticides
K1 women farmers
AB Farmers are among the most vulnerable populations because of the exposure to low levels of pesticides. Acetylcholinesterase and butyrylcholinesterase activities are considered as biomarkers of pesticides poisoning. However, biomarkers of oxidative stress are also playing an important role in toxicity of these contaminants. Further, increased activities of gamma-glutamyltransferase, alanine aminotransferase, urea and creatinine have been linked with hepatic and nephrotoxic cell damage, respectively. The aim of this study was to ascertain if the indirect exposure to pesticides leads to some biochemical parameter changes. Thus, cholinesterase activities, oxidative stress status (lipid and protein oxidation), hepatic function (AST and ALT levels), hormonal function (TSH, T4, FSH, LH and AMH), renal function (serum creatinine and urea), as well as possible subclinical kidney damage (urinary proteins and biomarkers of early kidney damage) were evaluated in farmer women who collect fruits and vegetables comparing with a group of women non-occupational exposed to pesticides but living in the same rural environment. Samples were taken periodically along one year to relate the observed effects to a chronic exposure. Our main results showed for the first time a subclinical kidney damage in a rural setting with indirect chronic exposure to pesticides.
YR 2021
FD 2021-05-31
LK http://hdl.handle.net/10668/17934
UL http://hdl.handle.net/10668/17934
LA en
DS RISalud
RD Apr 19, 2025