TY  - JOUR
AU  - Enguix-Riego, María Valle
AU  - Torroglosa, Ana
AU  - Fernández, Raquel María
AU  - Moya-Jiménez, María José
AU  - de Agustín, Juan Carlos
AU  - Antiñolo, Guillermo
AU  - Borrego, Salud
PY  - 2016
DO  - 10.1038/srep21160
UR  - http://hdl.handle.net/10668/9838
T2  - Scientific reports
AB  - Hirschsprung disease (HSCR) is attributed to a failure of neural crest derived cells to migrate, proliferate, differentiate or survive in the bowel wall during embryonic Enteric Nervous System (ENS) development. This process requires a wide and...
LA  - en
KW  - Alleles
KW  - Case-Control Studies
KW  - Child, Preschool
KW  - DNA (Cytosine-5-)-Methyltransferases
KW  - Down-Regulation
KW  - E1A-Associated p300 Protein
KW  - Enteric Nervous System
KW  - Female
KW  - Gene Expression Regulation
KW  - Genetic Predisposition to Disease
KW  - Genetic Variation
KW  - Genotype
KW  - Hirschsprung Disease
KW  - Humans
KW  - Infant
KW  - Male
KW  - Microsatellite Repeats
KW  - Neural Stem Cells
KW  - PAX6 Transcription Factor
KW  - Promoter Regions, Genetic
KW  - Protein Binding
KW  - Transcription Factors
TI  - Identification of different mechanisms leading to PAX6 down-regulation as potential events contributing to the onset of Hirschsprung disease.
TY  - research article
VL  - 6
ER  -