RT Journal Article
T1 The Epigenetics of Glioma Stem Cells: A Brief Overview
A1 Valor, Luis M.
A1 Hervás-Corpión, Irati
K1 Glioblastoma
K1 Histone
K1 DNA
K1 Methylation
K1 Acetylation
K1 Polycomb
K1 H3.3
K1 HDACi
K1 Histonas
K1 ADN
K1 Metilación
K1 Acetilación
AB Glioma stem cells (GSCs) are crucial in the formation, perpetuation and recurrence of glioblastomas (GBs) due to their self-renewal and proliferation properties. Although GSCs share cellular and molecular characteristics with neural stem cells (NSCs), GSCs show unique transcriptional and epigenetic features that may explain their relevant role in GB and may constitute druggable targets for novel therapeutic approaches. In this review, we will summarize the most important findings in GSCs concerning epigenetic-dependent mechanisms.
PB Frontiers
YR 2020
FD 2020-12-02
LK http://hdl.handle.net/10668/3546
UL http://hdl.handle.net/10668/3546
LA en
NO Valor LM, Hervás-Corpión I. The Epigenetics of Glioma Stem Cells: A Brief Overview. Front Oncol. 2020 Dec 2;10:602378
DS RISalud
RD Apr 6, 2025