RT Journal Article
T1 Psychosis and Dandy-Walker syndrome: a case report and review of the literature.
A1 Porras Segovia, Alejandro
A1 Guerrero-Jiménez, Margarita
A1 Carrillo de Albornoz Calahorro, Carmen Maura
A1 Gutierrez-Rojas, Luis
K1 cerebellar vermis
K1 cerebral ventricles
K1 psychotic disorders
K1 schizophrenia
K1 schizophrenia spectrum and other psychotic disorders
AB Dandy-Walker syndrome (DWS) is a group of brain malformations which sometimes present with psychotic symptoms. We present the case of a patient diagnosed with Dandy-Walker variant who presented with schizophrenia-like psychosis. A man in his 30s was admitted to an acute psychiatric unit presenting with persecutory delusions, auditory hallucinations and violent behaviour. The MRI performed showed the typical alterations of Dandy-Walker variant: vermian hypoplasia and cystic dilatation of the fourth ventricle. He also suffered from mild intellectual disability. After being treated with olanzapine 10 mg/d for a month, his psychotic symptoms greatly improved and he was discharged. In conclusion, DWS may cause psychosis through a dysfunction in the circuit connecting prefrontal, thalamic and cerebellar areas. The association between these two conditions may contribute to the understanding of the aetiopathogenesis of schizophrenia.
SN 2517-729X
YR 2021
FD 2021-04-14
LK http://hdl.handle.net/10668/17736
UL http://hdl.handle.net/10668/17736
LA en
DS RISalud
RD Apr 6, 2025