TY  - JOUR
AU  - Lorenzo, Petra I
AU  - Fuente-Martín, Esther
AU  - Brun, Thierry
AU  - Cobo-Vuilleumier, Nadia
AU  - Jimenez-Moreno, Carmen María
AU  - G Herrera Gomez, Irene
AU  - López Noriega, Livia
AU  - Mellado-Gil, José Manuel
AU  - Martin-Montalvo, Alejandro
AU  - Soria, Bernat
AU  - Gauthier, Benoit R
PY  - 2015
DO  - 10.1038/srep15672
UR  - http://hdl.handle.net/10668/2249
T2  - Scientific Reports
AB  - PAX4 is a key regulator of pancreatic islet development whilst in adult acute overexpression protects β-cells against stress-induced apoptosis and stimulates proliferation. Nonetheless, sustained PAX4 expression promotes β-cell dedifferentiation and...
LA  - en
PB  - Nature Publishing Group
KW  - Cell growth
KW  - ndocrine system and metabolic diseases
KW  - Aumento de la célula
KW  - Enfermedades metabólicas
KW  - Enfermedades del sistema endocrino
KW  - Medical Subject Headings::Anatomy::Digestive System::Pancreas::Islets of Langerhans
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Dedifferentiation
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Luminescent Proteins::Green Fluorescent Proteins
KW  - Medical Subject Headings::Anatomy::Cells::Endocrine Cells::Enteroendocrine Cells::Insulin-Secreting Cells
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Peptide Hormones::Pancreatic Hormones::Insulins
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
TI  - PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet.
TY  - research article
ER  -