RT Journal Article T1 Prognostic Significance of Lung and Cava Vein Ultrasound in Elderly Patients Admitted for Acute Heart Failure: PROFUND-IC Registry Analysis. A1 Pérez-Herrero, Sara A1 Lorenzo-Villalba, Noel A1 Urbano, Elena A1 Sánchez-Sauce, Beatriz A1 Aguilar-Rodríguez, Fernando A1 Bernabeu-Wittel, Máximo A1 Garcia-Alonso, Rocio A1 Soler-Rangel, Llanos A1 Trapiello-Valbuena, Francisco A1 Garcia-García, Alejandra A1 Casas-Rojo, Jose Manuel A1 Beltrán-Romero, Luis A1 De Jorge-Huerta, Lucia A1 Molina-Puente, Juan Igor A1 Andrès, Emmanuel A1 Iguarán-Bermúdez, Rosario A1 Méndez-Bailón, Manuel K1 B lines K1 clinical ultrasound K1 heart failure K1 inferior vena cava K1 mortality AB Introduction: Heart failure is an extremely prevalent disease in the elderly population of the world. Most patients present signs and symptoms of decompensation of the disease due to worsening congestion. This congestion has been clinically assessed through clinical signs and symptoms and complementary imaging tests, such as chest radiography. Recently, pulmonary and inferior vena cava ultrasound has been shown to be useful in assessing congestion but its prognostic significance in elderly patients has been less well evaluated. Objectives: This study aims to compare the clinical and radiological characteristics and predictive values for mortality in patients admitted for heart failure through the determination of B lines by lung ultrasound and the degree of collapsibility of the inferior vena cava (IVC). Secondarily, the study aims to assess the prediction of 30-day mortality based on the diameter of the IVC by means of the ROC curve. Methods: This is an observational cohort study based on data collected in the PROFUND-IC study, a nationwide multicentric registry of patients admitted with decompensated heart failure. Data were collected from these patients between October 2020 and April 2022. Results: A total of 482 patients were entered into the PROFUND-IC registry between October 2020 and April 2022. Bedside clinical ultrasound was performed during admission in 301 patients (64.3%). The number of patients with more than 6 B-lines on lung ultrasound amounted to 194 (66%). Statistically significant differences in 30-day mortality (22.1% vs. 9.2%; p = 0.01) were found in these patients. The sum of patients with IVC collapsibility of less than 50% amounted to 195 (67%). Regarding prognostic value, collapsibility data were significant for the number of admissions in the last year (12.5% vs. 5.5%; p = 0.04), in-hospital mortality (10.1% vs. 3.3%, p = 0.04) and 30-day mortality (22.6% vs. 8.1%; p SN 2077-0383 YR 2022 FD 2022-08-05 LK http://hdl.handle.net/10668/21329 UL http://hdl.handle.net/10668/21329 LA en DS RISalud RD Apr 19, 2025