RT Journal Article
T1 Prognostic Significance of Incidental Deep Vein Thrombosis in Patients with Cancer Presenting with Incidental Pulmonary Embolism.
A1 Barca-Hernando, Maria
A1 Ortega-Rivera, Rocio
A1 Lopez-Ruz, Sergio
A1 Elias-Hernandez, Teresa
A1 Asensio-Cruz, Maria Isabel
A1 Marin-Romero, Samira
A1 Toral, Javier
A1 Montero, Emilio
A1 Sanchez, Veronica
A1 Arellano, Elena
A1 Sanchez-Diaz, Jose Maria
A1 Real-Dominguez, Macarena
A1 Otero-Candelera, Remedios
A1 Jara-Palomares, Luis
K1 incidental
K1 mortality
K1 neoplasm
K1 prognosis
K1 pulmonary embolism
K1 venous thromboembolism
AB In symptomatic acute pulmonary embolism (PE), the presence of deep vein thrombosis (DVT) is a risk factor for 30- and 90-day mortality. In patients with cancer and incidental PE, the prognostic effect of concomitant incidental DVT is unknown. In this retrospective study, we examined the effect of incidental DVT on all-cause mortality in such patients. Adjusted Cox multivariate regression analysis was used for relevant covariates. From January 2010 to March 2018, we included 200 patients (mean age, 65.3 ± 12.4 years) who were followed up for 12.5 months (interquartile range 7.4-19.4 months). Of these patients, 62% had metastases, 31% had concomitant incidental DVT, and 40.1% (n = 81) died during follow-up. All-cause mortality did not increase in patients with DVT (hazard ratio [HR] 1.01, 95% confidence interval [CI] 0.43-2.75, p = 0.855). On multivariate analysis, weight (adjusted HR 0.96, 95% CI 0.92-0.99, p = 0.032), and metastasis (adjusted HR 10.26, 95% CI 2.35-44.9, p = 0.002) were predictors of all-cause mortality. In conclusion, low weight and presence of metastases were associated with all-cause mortality, while presence of concomitant DVT was unrelated to poorer survival.
SN 2072-6694
YR 2020
FD 2020-08-13
LK https://hdl.handle.net/10668/27493
UL https://hdl.handle.net/10668/27493
LA en
DS RISalud
RD Apr 7, 2025