TY - JOUR AU - Galindo-Moreno, María AU - Giráldez, Servando AU - Limón-Mortés, M Cristina AU - Belmonte-Fernández, Alejandro AU - Reed, Steven I AU - Sáez, Carmen AU - Japón, Miguel Á AU - Tortolero, Maria AU - Romero, Francisco PY - 2019 DO - 10.1096/fj.201900885R UR - http://hdl.handle.net/10668/14294 T2 - FASEB journal : official publication of the Federation of American Societies for Experimental Biology AB - Eukaryotic cells have developed sophisticated mechanisms to ensure the integrity of the genome and prevent the transmission of altered genetic information to daughter cells. If this control system fails, accumulation of mutations would increase risk... LA - en KW - FBXW7 inhibitors KW - cancer KW - proliferation KW - ubiquitylation KW - Animals KW - COS Cells KW - Cell Line KW - Cell Line, Tumor KW - Cell Proliferation KW - Chlorocebus aethiops KW - DNA Damage KW - F-Box Proteins KW - F-Box-WD Repeat-Containing Protein 7 KW - HCT116 Cells KW - HEK293 Cells KW - Humans KW - Mutation KW - Phosphorylation KW - Protein Domains KW - Proteolysis KW - Tumor Suppressor Protein p53 KW - Ubiquitin-Protein Ligases KW - Ubiquitination TI - SCF(FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage. TY - research article VL - 33 ER -