RT Journal Article
T1 GOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma.
A1 Luna, Javier
A1 Bobo, Andrea
A1 Cabrera-Rodriguez, Joaquín José
A1 Pagola, María
A1 Martín-Martín, Margarita
A1 Ruiz, María Ángeles González
A1 Montijano, Miguel
A1 Rodríguez, Aurora
A1 Pelari-Mici, Lira
A1 Corbacho, Almudena
A1 Moreno, Marta
A1 Couñago, Felipe
K1 Chemotherapy
K1 Malignant pleural mesothelioma
K1 Radiation techniques
K1 Radiotherapy
K1 Reradiation
K1 Surgery
AB Malignant pleural mesothelioma (MPM) is a rare tumor with poor prognosis and rising incidence. Palliative care is common in MPM as radical treatment with curative intent is often not possible due to metastasis or extensive locoregional involvement. Numerous therapeutic advances have been made in recent years, including the use of less aggressive surgical techniques associated with lower morbidity and mortality (e.g., pleurectomy/decortication), technological advancements in the field of radiotherapy (intensity-modulated radiotherapy, image-guided radiotherapy, stereotactic body radiotherapy, proton therapy), and developments in systemic therapies (chemotherapy and immunotherapy). These improvements have had as yet only a modest effect on local control and survival. Advances in the management of MPM and standardization of care are hampered by the evidence to date, limited by high heterogeneity among studies and small sample sizes. In this clinical guideline prepared by the oncological group for the study of lung cancer of the Spanish Society of Radiation Oncology, we review clinical, histologic, and therapeutic aspects of MPM, with a particular focus on all aspects relating to radiotherapy, including the current evidence base, associations with chemotherapy and surgery, treatment volumes and planning, technological advances, and reradiation.
SN 2218-4333
YR 2021
FD 2021
LK https://hdl.handle.net/10668/27594
UL https://hdl.handle.net/10668/27594
LA en
DS RISalud
RD Apr 6, 2025