TY - JOUR AU - Tejedo, J R AU - Tapia-Limonchi, R AU - Mora-Castilla, S AU - Cahuana, G M AU - Hmadcha, A AU - Martin, F AU - Bedoya, F J AU - Soria, B PY - 2010 DO - 10.1038/cddis.2010.57 UR - http://hdl.handle.net/10668/2255 T2 - Cell Death & Disease AB - Nitric oxide (NO) is an intracellular messenger in several cell systems, but its contribution to embryonic stem cell (ESC) biology has not been characterized. Exposure of ESCs to low concentrations (2-20 μM) of the NO donor diethylenetriamine NO... LA - en PB - Nature Publishing Group KW - Embryonic stem cell KW - Leukemia Inhibitory Factor KW - Differentiation KW - Self-renewal KW - Nitric Oxide KW - Células madre embrionarias KW - Factor Inhibidor de Leucemia KW - Diferenciación celular KW - Óxido Nítrico KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Antigens, Differentiation::Antigens, CD::Antigens, CD15 KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Embryonic Stem Cells KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Homeodomain Proteins KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Nitrogen Oxides::Nitric Oxide KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-NH2 Group Donors::Amino Acid Oxidoreductases::Nitric Oxide Synthase::Nitric Oxide Synthase Type III KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::POU Domain Factors::Octamer Transcription Factors::Octamer Transcription Factor-3 KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::Polyamines KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::SOX Transcription Factors::SOXB1 Transcription Factors KW - Medical Subject Headings::Organisms::Eukaryota::Animals TI - Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival. TY - research article ER -