RT Journal Article
T1 Advances and highlights in asthma in 2021.
A1 Agache, Ioana
A1 Eguiluz-Gracia, Ibon
A1 Cojanu, Catalina
A1 Laculiceanu, Alexandru
A1 Del-Giacco, Stefano
A1 Zemelka-Wiacek, Magdalena
A1 Kosowska, Anna
A1 Akdis, Cezmi A
A1 Jutel, Marek
K1 Asthma
K1 Biomarkers
K1 Endotypes
K1 Exacerbations
K1 Guidelines
AB Last year brought a significant advance in asthma management, unyielding to the pressure of the pandemics. Novel key findings in asthma pathogenesis focus on the resident cell compartment, epigenetics and the innate immune system. The precision immunology unbiased approach was supplemented with novel tools and greatly facilitated by the use of artificial intelligence. Several randomised clinical trials and good quality real-world evidence shed new light on asthma treatment and supported the revision of several asthma guidelines (GINA, Expert Panel Report 3, ERS/ATS guidelines on severe asthma) and the conception of new ones (EAACI Guidelines for the use of biologicals in severe asthma). Integrating asthma management within the broader context of Planetary Health has been put forward. In this review, recently published articles and clinical trials are summarised and discussed with the goal to provide clinicians and researchers with a concise update on asthma research from a translational perspective.
PB John Wiley & Sons
YR 2021
FD 2021-08-09
LK http://hdl.handle.net/10668/18379
UL http://hdl.handle.net/10668/18379
LA en
NO Agache I, Eguiluz-Gracia I, Cojanu C, Laculiceanu A, Del Giacco S, Zemelka-Wiacek M, et al. Advances and highlights in asthma in 2021. Allergy. 2021 Nov;76(11):3390-3407
DS RISalud
RD Apr 7, 2025