TY  - JOUR
AU  - Sastre-Moreno, Guillermo
AU  - Pryor, John M
AU  - Díaz-Talavera, Alberto
AU  - Ruiz, José F
AU  - Ramsden, Dale A
AU  - Blanco, Luis
PY  - 2017
DO  - 10.1093/nar/gkx625
UR  - http://hdl.handle.net/10668/11644
T2  - Nucleic acids research
AB  - The non homologous end-joining (NHEJ) pathway of double-strand break (DSB) repair often requires DNA synthesis to fill the gaps generated upon alignment of the broken ends, a complex task performed in human cells by two specialized DNA polymerases,...
LA  - en
KW  - Arginine
KW  - Conserved Sequence
KW  - DNA End-Joining Repair
KW  - DNA-Directed DNA Polymerase
KW  - Electrophoretic Mobility Shift Assay
KW  - Glycine
KW  - Humans
KW  - Models, Molecular
KW  - Mutagenesis
KW  - Mutation, Missense
KW  - Neoplasm Proteins
KW  - Oligodeoxyribonucleotides
KW  - Point Mutation
KW  - Protein Conformation
KW  - Protein Domains
KW  - Sequence Alignment
KW  - Sequence Homology, Amino Acid
TI  - Polμ tumor variants decrease the efficiency and accuracy of NHEJ.
TY  - research article
VL  - 45
ER  -