RT Journal Article T1 [Heart murmur in children less than 2 years-old: looking for a safe and effective referral strategy]. T2 Soplo cardíaco en menores de 2 años: buscando una estrategia de derivación eficiente y segura. A1 Rodríguez-González, Moisés A1 Alonso-Ojembarrena, Almudena A1 Castellano-Martínez, Ana A1 Estepa-Pedregosa, Lorena A1 Benavente-Fernández, Isabel A1 Lubián López, Simon P K1 Cardiopatías congénitas K1 Congenital heart disease K1 Echocardiography K1 Ecocardiografía K1 Heart murmur K1 Soplo cardiaco AB Current guidelines in Spain recommend performing transthoracic echocardiography (TTE) in all children under 2 years of age with a heart murmur. In 2014, the American Paediatric Association published the first appropriate use criteria (AUC) for outpatient paediatric transthoracic echocardiography (TTE) to promote its cost-efficient use. The aim of this article is to analyse the AUC and other clinical factors as predictors of congenital heart disease (CHD) in children less than 2 years of age with a heart murmur, and to develop a safe and efficient referral strategy. Case-control study conducted with children less than 2 years of age, referred from Paediatric Primary Care to Paediatric Cardiology during a 4-year study. A predictive model for CHD was determined using multivariate analysis. A total of 688 patients were included, with 129 (19%) cases of CHD. An age less than 3 months (adjusted odds ratio [ORa] 3.8 [1.5-8.4], p=.030) and fulfilling AUC (ORa 16.3 [9.4-28.3], p To refer children less than 3 months old, fulfilling AUC, without a concurrent infection, or without negative neonatal pulse oximetry screening, is a safe and efficient strategy for the management of heart murmur in children under 2 years of age. YR 2018 FD 2018-05-24 LK http://hdl.handle.net/10668/12510 UL http://hdl.handle.net/10668/12510 LA es DS RISalud RD Apr 7, 2025